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If you are concerned about our long term toxic exposure you'll find this interesting

12/5/2020

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This is repost is from Lara Adler, instagram environmentaltoxinsnerd Link to article http://linktr.ee/environmentaltoxinsnerd 

A lot of times when people talk about chemicals & health effects, we hear folks say stuff like "these chemicals have already been tested and have been found to be safe."⁠⠀
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Let's explore: ⁠⠀
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Traditional toxicology studies typically look at higher levels of exposure than we're used to getting, & they work backwards to find the "safe" level. When they find a level that does not produce an adverse effect (think: changes in organ weight, cancer, death), they establish the No Observed Adverse Effect Level (NOAEL). ⁠⠀
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Then some safety factors are added to reach the "reference dose" or the dose at which exposures are *presumed* safe. Once established, research into exposure levels below it STOPS, and that reference dose is rarely tested directly.⁠⠀
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And levels FAR below the NOAEL, ie, levels that reflect normal human exposure, are almost never tested! ⁠They are just ASSUMED to be safe. ⁠⠀
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While many substances do indeed follow what's known as a monotonic dose-response curve (ie, it's linear and predictable) endocrine-disrupting chemicals don't play that way. ⁠⠀
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The U-shaped graph in this post is an example of a non-monotonic or non-linear dose-response curve; at very very low levels, FAR below what traditional toxicology examines, you can see a LARGER response. ⁠⠀
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This matters because it means that, at least for EDC's, we cannot predict, or *assume* to know their behaviour based on high-dose testing unless we ACTUALLY and accurately test. ⁠⠀
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And yet that's just what toxicology does, it ASSUMES the line of the curve is always linear - without testing to confirm. ⁠⠀
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Why is this important to know?⁠⠀
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Because the #1 response to talking about chemicals is "the amount is so small it doesn't matter"!!⁠⠀
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If you understand, and can clearly articulate this concept, you'll do a dang better job at talking toxins with your clients, patients, or customers! ⁠⠀
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This is a core piece of the conversation about why chemical exposures matter which is why this topic is covered extensively inside my Talking Toxins professional course. ⁠⠀
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Thousands of health professionals have already been through this program! Check the linkinbio to learn more about it!


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